Monday, July 13, 2009

Drug Delivery

Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications

Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications presents an overview of the most recent applications of lipospheres primarily in the field of medicine, pharmaceutics and biotechnology. Included are chapters on preparation, characterization, delivery (of peptides, proteins, vaccines, nucleic acids) therapeutic applications to different systems and suggestions for further research. Including numerous illustrations, tables and photos, this book provides procedures for specific applications and biological systems and shows lipospheres as a technical solution to various problems associated with controlled release of biochemicals.

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Handbook of Pharmaceutical Controlled Release Technology


Cambridge Scientific, Inc., MA. Review the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices and membrane-controlled reservoir, bioerodible, and pendant chain systems. Expanded-outline format.

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Encyclopedia of Pharmaceutical Technology, Volume 20

AAI, Inc., Wilmington, NC. An encyclopedia of pharmaceutical technology, offering a collection of entries on a number of subjects, from drug delivery to process chemistry in the pharmaceutical industry. Lists the contents for all 20 volumes in the set. DNLM: Chemistry, Pharmaceutical-encyclopedias.
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This volume provides coverage assisted transdermal and topical delivery by mechanisms of iontophoresis, electroosmosis and electroporation. Other topics discussed are human and clinical studies with iontophoresis, such As Delivery Of Peptides, Proteins And Oligonucleotides, And Other developments.
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Drug Delivery Systems, Second Edition


Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments. Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both industry and academia. New in this edition: · Chapter focusing on novel technologies and their global outlook · Coverage of electronically controlled drug delivery · Macrocapsules and nanoparticles in drug targeting · Drug nanocrystals and other new delivery systems · Updated information on liposomes as carriers Written in a straightforward, clear, and concise manner, the author provides a global perspective on current and future advances and market opportunities. Drug Delivery Systems, Second Edition answers the need for comprehensive information in a single resource for anyone venturing into this area of drug development.
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Nanotherapeutics: Drug Delivery Concepts in Nanoscience

An important and exciting aspect in the newly developing field of nanomedicine is the use of nanoparticle drug delivery systems allowing for innovative therapeutic approaches. Due to their small size, these drug delivery systems are promising tools in therapeutic approaches such as selective or targeted drug delivery towards a specific tissue or organ, enhanced drug transport across biological barriers, and intracellular drug delivery.
This timely book provides an overview of possible therapeutic applications. The first part of the book highlights general properties of and phenomena observed with nanoparticles, and the subsequent consequences for applications in drug delivery. The second part focuses on the therapeutic approaches that are possible through the use of nanoparticles, with each chapter discussing a specific disease (e.g. diabetes, cancer, inflammation, etc.) and the relevant therapeutic approaches based on the design of nanoparticulate drug delivery systems. Written in a concise manner, readers will gain an insight into the basics of nanoparticle preparation as well as a more detailed account of what is therapeutically feasible by using nanoparticle approaches.
Contents: General Aspects of Nanotherapeutics: Nanocarriers in Drug Delivery - Design, Manufacture and Physicochemical Properties (C Schmidt & A Lamprecht); Transport Across Biological Barriers (N Nafee et al.); Targeting Approaches (S Cammas-Marion); Disease-Related Approaches by Nanotherapeutics: Nanoscale Cancer Therapeutics (Y Pellequer & A Lamprecht); Nanotherapeutics for Skin Diseases (N Atrux-Tallau et al.); Nanoparticles for Oral Vaccination (J M Irache et al.); Nanoparticles: Therapeutic Approaches for Bacterial Diseases (B Moulari); Nanoparticle Therapy in Parasites Diseases: Possibility and Reality! (M Larabi); Nanocarriers in the Therapy of Inflammatory Disease (A Lamprecht).
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Delivery System Handbook for Personal Care and Cosmetic Products :
Technology, Applications and Formulations



Novel delivery systems designed to facilitate the use of “fountain of youth” and other functional actives is an idea whose time has come. In a rapidly growing global market eager for products that really work, accelerating market pull and technology push forces have set the stage for this Foundation text. This “must have” book is the first volume of a new series entitled “Breakthroughs in Personal Care and Cosmetic Technology.” It has been carefully designed for training, development, and the empowerment of synergistic technology transfer across the personal care, cosmetic, and pharmaceutical industries.
This book is intended to cause a breakthrough in effective communication and interaction among technology and marketing functions. It is a showcase for understanding, using, and marketing the technology of why and how delivery systems work, as well as current, emerging/potential applications and working formulations. Each chapter is written by one or more experts in the field. A wide range of companies serving the global marketplace are represented. These companies offer numerous types of delivery systems containing highly desirable functional actives, delivery system technology development services, and opportunities for technology licensing, mergers, and acquisitions. A unique feature of the book is the use of Mind Map™ technology to capture and present the essence of the inner-thinking of over 80 authors in a Book-at-a-Glance Executive Overview section. This section has been specifically designed to powerfully impact decision making leading to the development of innovative product differentiation in a global context.
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Assessing Bioavailablility of Drug Delivery Systems: Mathematical Modeling


This book introduces mathematical modeling methods for calculating the profiles of plasma levels obtained with controlled release dosage forms and provides examples and case studies to illustrate the techniques employed. The mathematical models developed by the author are particularly powerful because they account for such major parameters as the kinetics of drug release controlled by diffusion or by erosion, and the kinetics of absorption into and elimination out of the plasma. They are also able to solve the problem of determining the drug level in plasma as a result of patient non-compliance, incorrect dosage, and incorrect frequency, and to determine the best dosage forms necessary for therapy.

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